Why many non-Westerners reject the gospel

Missionaries to Muslims often report resistance to the gospel message – not because Muslims reject Jesus as a great prophet, but because the Qur’an denies the doctrines of original sin and the atonement.
The idea of natural-born sinners runs counter to the Islamic belief that man is basically good but ignorant of Allah’s will. This may be overcome by repeating the shahada – “There is no god but Allah; Muhammad is the Messenger of Allah” – and by embracing the five pillars of Islam.
In addition, Muslims deny Jesus’ substitutionary death because they cannot believe Allah would allow his second greatest prophet to suffer shame on a Roman cross.
In other words, many Muslims reject the gospel because it does not align with their cultural perspective that stresses shame and honor rather than guilt and innocence.
So, how can Christians, who embrace the doctrines of original sin and the substitutionary death of Jesus, present the gospel cross-culturally? Is it even possible?
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A few years ago I joined leaders of a Christian non-profit organization in a meeting with executives of a Tennessee TV station. They were preparing to launch a new program catering to the LGBT community. We asked them to reconsider.
r – 12 merchandise of gold, silver, precious stones, and pearls; fine fabrics of linen, purple, silk, and scarlet; all kinds of fragrant wood products; objects of ivory; objects of expensive wood, brass, iron, and marble; 13 cinnamon, spice, incense, myrrh, and frankincense; wine, olive oil, fine wheat flour, and grain; cattle and sheep; horses and carriages; and slaves and human lives. 14 The fruit you craved has left you. All your splendid and glamorous things are gone; they will never find them again.